Porous is being supported by the European Union through the EFRE Project.

Supported by the EFRE Project.

As part of a ProFIT sponsorship, Porous will develop innovative bone ultrasound Imaging technologies for the early detection of osteoporosis. The planned product consists of patented software in combination with a certified ultrasound device, which for the first time makes it possible to detect macro- and microstructural as well as viscoelastic bone changes associated with an increase in the risk of fragility fractures non-invasively and without ionizing X-rays using an ultrasound scan.
In parallel, a health technology analysis is being carried out as part of a Gründung Innovativ project. Within the scope of this analysis, a systematic evaluation for PoroUS is to be developed, which covers both the direct and the indirect effects of the technology. Consequently, social, ethical and/or economic consequences will be analyzed in addition to medical ones.

Osteoporosis, a global health challenge

Osteoporosis accounts for more days in the hospital than breast cancer, heart attack, diabetes, and other diseases. Due to this fact, the cost that osteoporosis imposes on healthcare budgets is staggering. The economic burden of incident and prior fragility fractures in 2019 in Europe was estimated at €57 billion* (±US$64 billion), while in 2015, the United States spent US$20 billion. A staggering total annual cost of well over US$80 billion and growing.

*source: www.ncbi.nlm.nih.gov/pmc/articles/PMC8789736/

Early detection is vital

Current measurement methods cannot detect the onset of osteoporosis but rather approximate the bone-loss associated relative fracture risk, typically at advanced stages of the disease progression. Early detection is vital because the highest fracture incidence is not seen in people diagnosed to have osteoporosis but in those diagnosed to be healthy or osteopenic (losing bone mass), rendering osteoporosis one of the most underdiagnosed diseases in the western world. Early detection technology to overcome this clinical need was not available, until today. 

Microstructure analysis of the cortical bone

The Porous solution uses quantitative ultrasound (QUS) technology with patented intelligent algorithms being able to measure the cortical bone quality to a microscopic pore level without radiation hazards. The intelligent algorithms overcome the limitations of ultrasound imaging in the bone where waves are scattered, making it impossible to analyze the cortical bone (micro) structure. This unique technology can measure for the first time not only the cortical thickness, but also the microscopic pores and pore-size distribution in human cortical bone of the peripheral skeleton.

Prevention of osteoporosis becomes a reality

Due to the use of ultrasound systems (mobile by design), this solution can be used anywhere in- or outside the hospital, e.g., primary care, elderly homes, or even pharmacies. It creates the ability to use the technology for prevention (screening); being able to diagnose patients already at the onset of osteoporosis.

The Porous core team

Bart Hendriks

Chief Executive Officer

Jonas Massmann

Chief Technology Officer

Kay Raum

Chief Scientific Officer

We are hiring!

To keep track with Porous’ rapid growth and developments, we are looking to fill several positions with highly skilled and driven experts. Click on the vacancies below to read the full profiles.